Linear Dreams

A Life Sciences Business Consultancy

We are a business consulting firm specialized on corporate strategy, business and corporate development, portfolio analysis and asset and deal valuation services for life sciences companies.

Our clients include publicly-traded and privately-held biotech companies, a not-for-profit research foundation, contract research organisations as well as international investors seeking to invest in life sciences companies.

June 21, 2018: Represented Shanghai Henlius Biotech to initiate, structure and negotiate an exclusive license agreement with Accord Healthcare to develop and market HLX02, a proprietary trastuzumab biosimilar product of Shanghai Henlius in 72 countries from Europe, Middle East and North Africa (MENA) region and Commonwealth of Independent States (CIS). HLX02 is currently in a global, multi-center, double-blind, randomized Phase III trial.

February 14, 2018: Represented Shanghai Henlius Biotech to structure and negotiate an exclusive license agreement with Galaxy Biotech, LLC., in USA for the development and commercialization rights of novel monoclonal antibodies targeting the Death Receptor pathway (“Products”) in Greater China, including an option to expand to worldwide rights. The Products have first-in-class potential and target a broad range of solid and hematologic tumors.

December 20, 2017: Represented Shanghai Henlius Biotech to structure, negotiate and execute a licensing framework agreement whereby Jacobson Medical will be granted an exclusive right to develop and market HLX02, a proprietary trastuzumab biosimilar product of Shanghai Henlius in Hong Kong and Macau, and a right of first negotiation for certain emerging markets within the Association of Southeast Asian Nations (ASEAN). HLX02 is currently in a global, multi-center, double-blind, randomized Phase III study.

April 6, 2017: Represented Immune-Onc Therapeutics Inc. to establish a worldwide exclusive license and collaboration agreement with The University of Texas Health Science Center at Houston and The University of Texas Southwestern Medical Center.

March 28, 2017: Represented Immune-Onc Therapeutics Inc. to structure and negotiate an exclusive worldwide license agreement with Albert Einstein College of Medicine and Memorial Sloan Kettering Cancer Center.

November 2, 2016: Represented Shanghai Henlius Biotech to initiate, structure and negotiate an exclusive license agreement with Kolltan Pharmaceuticals, Inc., in USA for the development and commercialization rights of KTN0216 in Greater China and 15 countries in Asia Pacific region. KTN0216 is a novel antibody targeting c-MET discovered by Kolltan in preclinical development.

October 29, 2016: Represented Shanghai Henlius Biotech to structure and negotiate an exclusive license agreement with AbClon Inc., based in Korea for the development and commercialization rights of AC101 in Greater China, including an option to expand to worldwide rights. AC101 is an innovative antibody developed by AbClon targeting gastric cancer and breast cancer in preclinical development.

August 16, 2016: Represented Shanghai Henlius Biotech in the negotiation of an exclusive license agreement with Shanghai Jing Ze Biotech for the development and commercialization rights of HLX-05 in China. HLX-05, a cetuximab biosimilar developed by Shanghai Henlius Biotech, received IND approval for two indications by the China FDA.

May 14, 2016: Linear Dreams supports GF Xinde to close a Life Sciences Fund with Bay City Capital.

Cheni Kwok, Ph.D., CLP

Founder and Managing Partner

Dr. Kwok is a senior biopharmaceutical executive with broad operational expertise who has executed over 100 transactions including M&A, strategic partnerships, licensing, divestitures, spin-offs and project financing. Dr. Kwok is the Managing Partner and Founder of Linear Dreams LLC, a management consultancy for the life sciences industry. The firm’s engagements include search & evaluation of clinical-stage products, licensing, corporate strategy & portfolio planning, acquisition & financing due diligence, business development and valuation for 36 biopharmaceuticals companies, contract research & non-profit organizations, research institutes and investors in USA, Europe, China, Taiwan and Singapore. Dr. Kwok currently serves as the Head of Business Development Shanghai Henlius Biotech, Henlix Biotech and Immune-Onc as well as the Chief Business Officer of Fochon Pharma.

As Senior Vice President, Corporate Development at Poniard Pharmaceuticals Inc., Dr. Kwok established corporate and business development, strategic and commercial planning, new product planning, competitive intelligence and forecasting functions. Previously, she was Director of Business Development at Celera Genomics Inc., where she led the business development efforts for Celera's small molecule therapeutics, including the divestiture of the oncology pipeline (including Imbruvica® (ibrutinib)) to Pharmacyclics Inc. (now an AbbVie Company). Dr. Kwok held business development positions of increasing responsibility at Exelixis Inc., where she initiated multiple partnerships and served as the alliance manager for the GlaxoSmithKline PLC (GSK) collaboration. Prior to joining Exelixis Inc., she held various research management, technology assessment and alliance management roles at SmithKline Beecham PLC (now GSK).

Dr. Kwok received a bachelor's degree in biotechnology from the Imperial College of Science, Technology and Medicine, University of London, UK, a Ph.D. in human molecular genetics from the University of Cambridge, UK and has earned the Certified Licensing Professional (CLP) credential awarded by the Licensing Executives Society. At present, Dr. Kwok is the President of the Chinese-American Biopharmaceutical Society (CABS), board advisor of the Chinese Bioscience Association (CBA) and serves on the Standards, Admissions & Recertification committee of Certified Licensing Professional (CLP) and the California Chinese Unit Leadership Council of the American Cancer Society (CCU-ACS).

Dr. rer. nat. Jozsef Ludvig

Founder and Managing Partner

Dr. Ludvig is a Managing Partner of Linear Dreams LLC, a management consultancy and valuation software firm specialized in corporate strategy, business/corporate development, portfolio analysis, and valuation services for the life science industry.

Prior to founding Linear Dreams LLC, Dr. Ludvig worked as experimental physicist and senior design engineer at Lawrence Berkeley National Laboratory, the Stanford Linear Accelerator Center and several privately-held companies.

Dr. Ludvig received bachelor's and master's degrees in Physics from the University of Stuttgart, Germany and a doctorate degree in Physics from the University of Heidelberg, Germany, for developing real-time data processing algorithms for the ATLAS collaboration at CERN, the European Organization for Nuclear Research. Dr. Ludvig specializes in hardware & software development, data analysis and modeling.

Linear Dreams is a modern interpretation of "Direct Dreams" 直梦 or "Dreams of Direct Fulfillment," as cited in the Lunheng 论衡 or "Critical Essays" by Wang Chong 王充, a Chinese philosopher who lived during the Han Dynasty (27 AD to about 97 AD). "Direct Dreams," according to the philosopher, are those that show future events.

In "Critical Essays," Wang Chong demonstrated that his intellect was far ahead of his time. His essays exhibit his methodology of logical deduction and his courage to criticize the widely accepted beliefs of his peers.

Wang Chong was a strong supporter of naturalistic explanations and uncompromising rationality. Despite the lack of empirical science in his time, he called for evidence-based reasoning and decision making.

The modern world has proven Wang Chong right. Greatest success in science and business are achieved by application of rational intellectual principles that were already known to philosophers in East and West some 2000 years ago.

We strongly believe that in business, just as in science, empirical data provides the foundation to rational decision-making processes.